Established in 2014, the Product Development for Vaccines Advisory Committee (PDVAC) is an independent, standing committee of experts which provides external advice to WHO related to vaccine and monoclonal antibody candidates for priority infectious disease pathogens, generally at the stage of early clinical development. The committee’s remit covers disease areas where there is, or may be, substantial disease burden in low and middle income countries (LMICs), where there is product development activity which may benefit from WHO guidance, or where novel platform technologies could expedite availability and access of vaccine products in LMICs.