A city’s most important asset is the health of its citizens. Yet 7 million premature deaths annually are attributed to air pollution, most in developing cities with rapid growth. In Ghana, WHO estimates over 28 000 premature deaths are due to the combined effects of household and ambient air pollution. Led by WHO, Urban Health Initiative in Accra equipped local and national stakeholders, within and beyond the health sector, with tools for the comprehensive assessment of policies related to air pollution – driving demand for multi-sector action on health at the local level.