Why the HIV epidemic is not over
WHO announced the “3 by 5” initiative with the aim of providing HIV treatment to 3 million people in low- and middle-income countries by 2005. “The ‘3 by 5’ initiative was the most ambitious public health programme ever launched, which would increase 15-fold the number of people receiving life-saving treatment in some of the poorest countries of the world, in just three years”, says Dr Ball.
Despite continued, unprecedented expansion of access to HIV treatment in the early 2010s, there was growing concern that we weren’t moving fast enough, and that we weren’t getting ahead of the epidemic. In 2014, the “90-90-90” targets were launched to galvanise further action. By 2020, the targets were that: 90% of all people living with HIV will know their HIV status; 90% of all people diagnosed with HIV infection will receive sustained antiretroviral therapy; and 90% of all people receiving antiretroviral therapy will achieve viral suppression.
In 1994 a study showed that providing antiretrovirals to pregnant women infected by HIV and a short course of treatment for the baby once born reduced transmission rates to below 5%, from 15-45% without treatment. The availability and coverage of ARVs to prevent HIV transmission from mother to children has been remarkable, with an estimated 80% of pregnant women with HIV able to access ARVs globally.
In 2015, WHO recommended the use of ARVs to prevent HIV acquisition – pre-exposure prophylaxis or PrEP – for people who do not have HIV but are at substantial risk. PrEP has contributed to reduce rates of new HIV infections among men who have sex with men, in some settings in high-income countries. However, PrEP is only starting to be available in low- and middle-income countries, where programmes are starting for men who have sex with men and transgender people in all regions, as well as sex workers, adolescent girls and young women in East and Southern Africa.
The theme of this World AIDS Day – Know Your Status – is important. One in four people with HIV don’t know that they have HIV. To bridge some critical gaps in the availability of HIV tests, WHO recommends the use of self-tests for HIV. WHO first recommended HIV self-testing in 2016, and now more than 50 countries have developed policies on self-testing. WHO, working with international organizations such as Unitaid and others, supported the largest HIV self-testing programmes in six countries in southern Africa. This programme is reaching people who have not tested themselves before, and is linking them to either treatment or prevention services. This World AIDS Day, WHO and the International Labour Organization will also announce new guidance to support companies and organizations to offer HIV self-tests in workplace.
People with HIV often have other infections – known as co-morbidities – such as TB or hepatitis. One in three deaths in people with HIV is from TB. Around 5 million people are living with both HIV and viral hepatitis. One in three people with HIV has heart disease. This has meant that HIV care has long needed joined-up care, although this doesn’t always happen in practice. “WHO is now promoting ‘person-centred’ health services to all people living with HIV, to meet their holistic health needs, not just their HIV infection – linking HIV services with those for TB, sexual and reproductive health, non-communicable diseases and mental health,” says Dr Hirnschall.
How do we do this? Outside sub Saharan Africa, 75% of new infections are among key populations and their partners. We need to act on these data and re-focus services to reach these populations at greatest risk. This will include addressing stigma and discrimination that continue to be barriers and providing services in and with communities. In 2016 the World Health Assembly adopted the WHO Global Health Sector Strategy on HIV, 2016–2021. The strategy provides new direction for the HIV response as it aims to fully integrate HIV into the broader health and development agenda of achieving universal health coverage by 2030 – where all people receive high-quality health services and medicines they need without experiencing financial hardship.
“The future of the HIV response will also require looking beyond HIV care provision and ensuring that the disease response is embedded in universal health coverage. Ending AIDS is unlikely to ever happen without Integrated health system that provide HIV prevention, diagnosis, and treatment as well as care with other essential health services. and support to other co-morbidities such as TB, NCDs and mental health at the community level. A people-centred, human rights based and holistic approach is crucial”, says Dr Naoko Yamamoto, Assistant Director-General for Universal Health Coverage and Health Systems, WHO.
“30 years after the first World AIDS Day campaign, we still cannot be complacent in our response to HIV,” says Dr Hirnschall.
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